Antec showed off its next flagship PC chassis, targeting enthusiasts, the P380. This full-tower can house E-ATX, SSI-CEB, HPTX, and XL-ATX motherboard types, apart from standard ATX and micro-ATX. It features 9 expansion slots. The frame is made of SECC-Steel, but the case features high-density polycarbonate panels, which look good (faux-aluminium), and work to absorb vibrations.

Drive bays on the P380 include two 5.25-inch, and eight 3.5-inch/2.5-inch drive trays, split between two cages, with the bottom 6-tray one being detachable, to free up 465 mm of room for some really long graphics cards (350 mm with the cage in place). Cooling system includes room for a 360 mm x 120 mm top radiator, and another one along the front panel, and a 120 mm rear exhaust. Front panel connectivity includes two each of USB 3.0 and USB 2.0/1.1 ports, and standard HDA audio jacks.