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TPU's F@H Team

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I've got my two 460's back online folding. If you recall I had issues with one of the cards (a Zotac) crapping out, even blue screening my rig. I've upped the PS from a 520 watt to a 650 watt corsair. I'm inching up the clocks oh so carefully and should be well north of 24K PPD real-soon-now.
 
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I hope you guys don't mind if I come back for the CC. I should have asked first.
 
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El Fiendo, are you coming back for the CC?

Would love to have him aboard, but he tends to post selectively nowadays.:cry:

Mike, you folding with us or those OCN flunkies?;)


All you have to do is blow on The Horn of Fiendo Summoning and then I generally show up and loiter around for 48-72 hours before sliding back into the shadows. Use it wisely though cause I'll sleep on your couch and play your video games. I always go half on ordered food though so its not all bad.
 
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All you have to do is blow on The Horn of Fiendo Summoning and then I generally show up and loiter around for 48-72 hours before sliding back into the shadows. Use it wisely though cause I'll sleep on your couch and play your video games. I always go half on ordered food though so its not all bad.

Thank you for making me laugh. :) Are you going to fold in the CC?
 

BUCK NASTY

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I hope you guys don't mind if I come back for the CC. I should have asked first.
You always welcome here, even though you've made questionable team choices in the past.:D

All you have to do is blow on The Horn of Fiendo Summoning and then I generally show up and loiter around for 48-72 hours before sliding back into the shadows. Use it wisely though cause I'll sleep on your couch and play your video games. I always go half on ordered food though so its not all bad.

I prefer to use the traditional method:laugh:

 

[Ion]

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I've just purchased a GTX460 for the Xeon setup--I'm thinking about buying a second one...we'll see...
 

Feänor

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Due to recent financial priority repositioning (what a nice way to say i need to repair my car...), most of my farm will have to go in the next few weeks. :shadedshu

Any folder interested in a 24 cores sr-2 or 970/g1.assassin rig should check in the next week for my sale thread to be updated (or just PM me). I'm still digging for each and every thing that could be worth a few bucks...

I do realize (the :nutkick: way) now that two standard closets can contain quite a few pc/watercooling bits and pieces...
 
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Thank you for making me laugh. :) Are you going to fold in the CC?

Well I was going to out of principle and team allegiance, but


this cemented it.

And Buck I've always been on team TPU, my name on HWC is where I test my hardware and any overclocks. That way any failed WUs go under their name and keep TPU clean and clear.

Muahahahaha


Edit: I see you browsing Bogi. First off :love:. Second off, I dislike you. Third off :love:.
 
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bogmali

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I've always been on team TPU, my name on HWC is where I test my hardware and any overclocks. That way any failed WUs go under their name and keep TPU clean and clear.


Don't try to sugarcoat your way out the fact that you fold for them:slap:

Wish Mmaakk was here to see this post:rolleyes:

Edit: And you knew I was to going to post as soon as I saw the Bat Signal
 
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Don't try to sugarcoat your way out the fact that you fold for them:slap:

Wish Mmaakk was here to see this post:rolleyes:

Edit: And you knew I was to going to post as soon as I saw the Bat Signal


YOUR MMAAKK CAN'T SAVE YOU NOW BOGI!


And to be fair I folded for TPU a heck of a lot more recently than HWC.
 

bogmali

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And to be fair I folded for TPU a heck of a lot more recently than HWC.

Quoting myself again just to make sure you understand:slap:

Don't try to sugarcoat your way out the fact that you fold for them

Edit: BUCK can I ban this guy for trolling even-though he is on your sub-forum?

:laugh::laugh::laugh:
 
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Fired up a Xeon 8 core with a 580 also should be good for at least another 50,000 PPD. :D
:toast:
 

[Ion]

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Fired up a Xeon 8 core with a 580 also should be good for at least another 50,000 PPD. :D
:toast:

Any idea what a dual-Xeon E5420 would do? Come competition time I could put that on FAH for a bit...
 
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All help is appreciated:toast:
 
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BUCK NASTY

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Edit: I see you browsing Bogi. First off :love:. Second off, I dislike you. Third off :love:.
LOL, not trying to diagnose, but appears a little Bipolar...;)

Gotta admit, I miss your witty, twisted sense of humor. Nice to have you back until you go underground again.

:toast:
 

[Ion]

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Well, I'll think about pulling it over to FAH for the duration of the contest--it's not running any of my AMD GPUs, so it wouldn't penalize my WCG performance too much :toast:
 
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Any idea what a dual-Xeon E5420 would do? Come competition time I could put that on FAH for a bit...

CC, 2 years ago, I had my son's i5-650 (4 threads) running at 4.0 GHz and it got 4-5000 PPD. Last year, I had it running at stock (3.2 GHz) and with the reduction in points for SMP, it was only getting 800 PPD. So my guesstimate would be well under 1000 PPD.
 

[Ion]

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CC, 2 years ago, I had my son's i5-650 (4 threads) running at 4.0 GHz and it got 4-5000 PPD. Last year, I had it running at stock (3.2 GHz) and with the reduction in points for SMP, it was only getting 800 PPD. So my guesstimate would be well under 1000 PPD.

I'm surprised by that--I tried out FAH briefly on a C2D in January and I was getting ~2.8-3.4k from it (2.8GHz, 6MB L2, 1GB single-channel RAM)
 
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Fired up a Xeon 8 core with a 580 also should be good for at least another 50,000 PPD. :D
:toast:

That 580 with a 900 core will do 46k by itself. :toast:
 
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Lovely news!

A single drug can shrink or cure human breast, ovary, colon, bladder, brain, liver, and prostate tumors that have been transplanted into mice, researchers have found. The treatment, an antibody that blocks a "do not eat" signal normally displayed on tumor cells, coaxes the immune system to destroy the cancer cells.

A decade ago, biologist Irving Weissman of the Stanford University School of Medicine in Palo Alto, California, discovered that leukemia cells produce higher levels of a protein called CD47 than do healthy cells. CD47, he and other scientists found, is also displayed on healthy blood cells; it's a marker that blocks the immune system from destroying them as they circulate. Cancers take advantage of this flag to trick the immune system into ignoring them. In the past few years, Weissman's lab showed that blocking CD47 with an antibody cured some cases of lymphomas and leukemias in mice by stimulating the immune system to recognize the cancer cells as invaders. Now, he and colleagues have shown that the CD47-blocking antibody may have a far wider impact than just blood cancers.

"What we've shown is that CD47 isn't just important on leukemias and lymphomas," says Weissman. "It's on every single human primary tumor that we tested." Moreover, Weissman's lab found that cancer cells always had higher levels of CD47 than did healthy cells. How much CD47 a tumor made could predict the survival odds of a patient.

To determine whether blocking CD47 was beneficial, the scientists exposed tumor cells to macrophages, a type of immune cell, and anti-CD47 molecules in petri dishes. Without the drug, the macrophages ignored the cancerous cells. But when the anti-CD47 was present, the macrophages engulfed and destroyed cancer cells from all tumor types.

Next, the team transplanted human tumors into the feet of mice, where tumors can be easily monitored. When they treated the rodents with anti-CD47, the tumors shrank and did not spread to the rest of the body. In mice given human bladder cancer tumors, for example, 10 of 10 untreated mice had cancer that spread to their lymph nodes. Only one of 10 mice treated with anti-CD47 had a lymph node with signs of cancer. Moreover, the implanted tumor often got smaller after treatment—colon cancers transplanted into the mice shrank to less than one-third of their original size, on average. And in five mice with breast cancer tumors, anti-CD47 eliminated all signs of the cancer cells, and the animals remained cancer-free 4 months after the treatment stopped.

A Weekly Chat on the Hottest Topics in Science Thursdays 3 p.m. EDT
"We showed that even after the tumor has taken hold, the antibody can either cure the tumor or slow its growth and prevent metastasis," says Weissman.

Although macrophages also attacked blood cells expressing CD47 when mice were given the antibody, the researchers found that the decrease in blood cells was short-lived; the animals turned up production of new blood cells to replace those they lost from the treatment, the team reports online today in the Proceedings of the National Academy of Sciences.

Cancer researcher Tyler Jacks of the Massachusetts Institute of Technology in Cambridge says that although the new study is promising, more research is needed to see whether the results hold true in humans. "The microenvironment of a real tumor is quite a bit more complicated than the microenvironment of a transplanted tumor," he notes, "and it's possible that a real tumor has additional immune suppressing effects."

Another important question, Jacks says, is how CD47 antibodies would complement existing treatments. "In what ways might they work together and in what ways might they be antagonistic?" Using anti-CD47 in addition to chemotherapy, for example, could be counterproductive if the stress from chemotherapy causes normal cells to produce more CD47 than usual.

Weissman's team has received a $20 million grant from the California Institute for Regenerative Medicine to move the findings from mouse studies to human safety tests. "We have enough data already," says Weissman, "that I can say I'm confident that this will move to phase I human trials."


This was posted by Black Panther in another thread so kudos to him for posting. If this works on humans. :toast:
 
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Norton

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Processor Ryzen 5900X- Ryzen 5950X- Ryzen 3950X and etc...
Motherboard Asrock X570 Extreme4- MSI X570S Tomahawk MAX WiFi- MSI B450M Bazooka Max and etc...
Cooling Noctua NH-U14S (dual fan)- EK 360 AIO with push/pull fans- Corsair H115i RGB Pro XT and etc...
Memory 2x16GB GSkill FlareX 3200/c14- 4x8GB Corsair Vengeance 3600/c16- 2x16GB Team 3600/c18 and etc..
Video Card(s) MSI Gaming RX 6800- Asus RTX 3070 TUF OC- MSI Ventus GTX 1660Ti and etc...
Storage Main PC (1TB WD SN850- 2TB PNY CS 3040- 2TB Seagate Firecuda) and etc...
Display(s) Main PC (2x24" Dell UltraSharp U2414H)
Case Phanteks P600s- Seasonic Q704- Fractal Meshify C and etc...
Audio Device(s) Logitech Z625 THX 2.1 speakers
Power Supply EVGA 750 G3- SeaSonic DGC 750- EVGA P2 850 and etc...
Mouse G300s
Keyboard Corsair K65
VR HMD N/A
Software Windows 10 Pro or Ubuntu
Benchmark Scores Why sit on the Bench when you can get in the game and Crunch!!!
That 580 with a 900 core will do 46k by itself. :toast:

That should put my new i7-920/2x580 rig at 90-100k ppd then! :rockout:

Hope to have it up and running by tomorrow evening at the latest.... tonight if I don't have too many projects this afternoon from the boss wife :eek:
 
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