Hey there,
@buffyvpsfan!
It's preferable to use specific NAS/RAID HDDs, because they can save you from rebuilding the array which often happens with regular desktop drives. The specific RAID-environment drives have different features and firmware with algorithms that optimize the performance, power and reliability of that drive. They are even tested to run in 24/7 environments. In contrast, the average desktop drives are not optimized for multi-drive systems which have higher noise and vibration levels. If such drives are added to a RAID system, this additional vibration can reduce the life span and reliability.
However, it really depends on what you intend to use the RAID for as
@Steevo mentioned. For example, a lot of video editing professionals prefer RAID-ing SSDs because of the intense work on raw files and the needed high speed. But it's a rather pricey configuration and most of the time unnecessary for other RAID users.
Since you are looking for speed, then RAID 0 (striping) is what would suit you best. It enhances performance, speed and all the storage capacity is usable unlike other RAID configurations, but it has no fault-tolerance and failure in just one disk can result in loss of all the data on the array. So I'd recommend not to keep anything important on it.
Hope this helped. Keep us posted with your decision!
SuperSoph_WD