Very tricky trickson - yes that system has no brain
On the 10.1, not sure what's it's doing for you though, but stability ? That's funny you mention 10.1 since it's causing ati's to crash.
( I've seen nvidia more stable for over a decade - it's not even close - there shouldn't ever be any hazy idea otherwise - even ati fans may have to NOT USE CCC - if they know what they're doing - they tell you everything is perfect, then you find out they won't use the included control panel from their fave card company... I'm sorry but that settles it right there. ) If someone tells me expert enthusiasts can make sure ati cards are rock stable - I'll agree.
It seems to me you can answer your own question just slap your 4850 from your profile in your second system.
(or maybe you're just trolling for giggles - and don't have a second system - who knows! )
WHATEVER.
" I already have a 4850 in my 680i board profile , now I want to do it to another - should I ? "
Oh boy it smells like BS to me.
Then you answer your own questions in the thread ... and respond already "figured out" on any point - LOL
Enjoy ripping out CCC, crashing on 10.1, etc etc... is all I have left to say.