Dell introduced its first AMD-based mainstream PC lineup in over 18 months. The company had stopped announcing AMD-based products as its CPU lineup were losing in competitiveness. The Inspiron 546, as American-Statesman's Kirk Ladendorf notes, "could signal a shift in the ongoing relationship between Dell and AMD, which has gone through warm and cold spells in recent years." Inspiron 546 represents one of Dell's most important desktop PC SKUs, that is extensively promoted online.
Priced in the US $270~$710 range, Inspiron 546 models come in four main configurations
, featuring Sempron, Athlon X2, Phenom X3, and Phenom X4 processors, with ATI Radeon HD 3200 series graphics. The chassis comes with 8 colour bezel types to choose from. It can further be customised with a variety of Dell monitors, HDD capacities, and memory amounts.