Originally Posted by cadaveca
Single rail units tend to have higher current limits, which facilitates having a system with high 12V usage. I can run my 7950s and 3770k on 450W single rail PSU, but not a 450W multi-rail PSU, since the rails do not provide enough power, and one is not used by VGAs due to how it's wired.
But that depends on how it's made anyway. As you said yourself, it isn't black or white.
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