Ok so I'm running a lowly 550Ti and have this GTS250 sitting doing nothing and I thought, why not dedicate it to PhysX for the one lousy game I pay that can use it. Problem is, I'm not sure if this 600 Watt PS is going to be able to handle the load. Now, let me say that while this PS is basically a no name-er, it is pretty solid, I even had a short on the 12v which took out a hard drive (flames and all) but the PS kept going like a champ. Though I may have to see if I can provide it with more airflow. Anyway, these are what I am working with: hec X-Power Pro 600 600W Continuous @ 40°C ATX12V V2.2 SLI Ready CrossFire Ready Power Supply MSI N250GTS-2D512-OCv2 GeForce GTS 250 512MB 256-bit GDDR3 PCI Express 2.0 x16 HDCP Ready SLI Support Video Card EVGA 01G-P3-1556-KR GeForce GTX 550 Ti (Fermi) FPB 1GB 192-bit GDDR5 PCI Express 2.0 x16 HDCP Ready SLI Support Video Card Plus 3 hard disk drives. I'm thinking probably no based on the supposed current requirements of te GTS250 but more input would be appreciated.