Hi, I hope you guys can help me out a little here. I have a mixed arsenal of nVidia cards which I intend to use for folding@home. I've no problem setting up multi-GPU folding but the purpose of this thread is to find out more about mixing of nVidia cards. I'm having a hard time finding people with similar experience, since most people would just run SLI, or if not, their folding setup run the same GC from the 1st to the last slot........ not possible in my case. My current successful setup is using MSI P55-GD65 + GTX260+ + GT220. Rig #2 is using Jetway X-Blue P45 with 9600GT. I placed the GT220 in there and it doesn't seem to detect. Now I've read somewhere that there is a problem having nVidia Geforce 9xxx series to be on the same machine as the Geforce GTxxxx series. How true is that? I'm giving myself a few tries on Rig #2 before I go try the GT220 on rig #3, which is an SLI board that currently has a GTS250 on it.