Couldn't really agree more with this. It just so happens with my case I was able to get the rads before the components without too much fuss or extra tubing. My suggestion is once the case is there and you have all the parts, sort of play around with mounting and routing ideas prior to making any tubing cuts. One thing that I find really can simplify a loops look is 45* and 90* fittings before the barbs. This allows you to direct the tubing at things rather than large round bends to make it to the barbs that stick straight off of the components of the loop.