I quite literally interpreted the title as Dodge RAM: Dualie or 4x4...... My brain isn't functioning right today, I was a little disappointed I will admit though. I have 4x8GB and I found that my overclock is less stable and I probably can't get 5Ghz if I wanted now because of it. Using 2x8GB will also leave you with room to expand. I would choose 2x8GB. oh, and Dualie all the way. Love the Cummins engine too.