Can I suggest you have a look at the GPU2 folding client at this link You will be contributing to much larger protein folding (they reserve the big ones for the GPU's) and getting about 10X the points that you will get with your CPU client. You can even run both the CPU and GPU clients at the same time. On my machine, when running the GPU client alone, my Core1 utilization goes up to 100% and Core2 remains idle. When I kick in the CPU folding Core1 remains at 100% and Core0 goes to about 70% utilization. Even in this state the system seems fine for wen browsing and such. If I want to game I just pause both clients and turn them back on when I am done.