The title is used to catch your eyes. My computer will go to sleep when left alone for some time obviously, but ever one in 7 times or so, will NOT wake up. To wake it up, I have to turn it off by the power button in the PS (no other way of turning it off works, not even cussing very loudly at it ) ASUS Crosshair iv (ROG) AMD Pii 945 4GB 1600 DDR3 (forget ramtype, but it checks out fine) quite a few hard drives, totaling up to about 10TB internal storage, 2x150GB in RAID-0 Thermaltake Soprano Case 2x5750 CFX (amazing, can still play everything today max with AA) Notable software: Windows 7 ULT AVG (not pro, computer checks out in malwarebytes and hijack this!) Fences) 1. There is power going to the computer, everything is lit up including the mouse, etc... Mouse will light up for just a second when click, like the computer is going to turn on, then goes off. 2. Computer passes all tests, and has been dusted out thoroughly. 3. Computer temperature maintains great, my airflow is amazing, nothing is overclocked (Hasn't been since this problem, and wont be again until the problem is fixed) 4. Behavior points to it being a motherboard issue, but then again im asking the many experts we have here at TPU to be sure. 5. There have been no known issues with this computer with me, or it's parts' previous owners. The buttons on the case, and the buttons on the motherboard (has 'start' and 'reset' on the motherboard) 6. No known pattern as far as I can tell in terms of what might cause this. 7. Works perfectly once the computer starts back up and resumes windows. Thank you very much in advance for your help everyone!