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Disinfection spreads antimicrobial resistance

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During the COVID-19 pandemic, the use of disinfectants, alcohol-based hand sanitizers, and antiseptic hand wash has surged. As a precaution, many authorities have also increased chlorine dosage in wastewater disinfection to achieve a free chlorine residual concentration greater than 6.5 mg/liter (1), despite evidence that a free chlorine residual of just above 0.5 mg/liter can completely inactivate human coronavirus (2). These chemicals can reach aquatic and terrestrial environments through direct discharge of wastewater into receiving waters. Disinfection protocols put in place to prevent COVID-19 should be limited to the minimum required to kill severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and weighed against their potential to increase antimicrobial resistance (AMR).

Disinfectants facilitate the bacterial acquisition of AMR, potentially the biggest global health challenge next to the COVID-19 pandemic (3). For example, antiseptic ingredients quaternary ammonium compounds (4), triclosan (5), chlorhexidine (6), and ethanol (7); chlorine-based disinfectants (8); and disinfection by-products (9) can promote the spread of AMR through mutation or horizontal gene transfer. Thus, current increases in disinfection practices may pose an environmental and public health risk by accelerating the spread of AMR.

Unlike human viruses, which cannot independently reproduce and rarely survive in the environment, bacteria can proliferate and persist, conceivably inheriting AMR over generations. The health of humans and animals is inextricably connected to the environment, potentially creating a cycle of AMR dissemination. Indeed, humans and animals can acquire AMR from the environment through food (10), water (11), and air (12).

From the One Health perspective, a robust risk assessment is necessary to evaluate the environmental and public health risks of increased disinfection and its role in mediating the spread of AMR, particularly in the long term. To reduce the release of disinfectants into the environment, policies should be enacted to reduce unnecessary fomite disinfection, reduce the chlorine load to maintain a free chlorine residual of just above 0.5 mg/liter (2), and dechlorinate treated effluent before discharge. These approaches may be critical to protecting the public from future health threats by slowing down the dissemination of AMR.


https://science.sciencemag.org/content/371/6528/474.1

http://www.awmc.uq.edu.au/science-letter-disinfection-spreads-antimicrobial-resistance

https://pubmed.ncbi.nlm.nih.gov/33510019/
 
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Yep. Disinfectants are effectively evolution in fast action. It's the reason we need to end this as fast as possible.
 
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not to mention they screw up your skin and often have carcinogens in em depending on which one used. hand sanitizer makes my hands itch like mad.
 
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Hi,
Yeah I wear gloves good mechanic type, let them get all the crazy sterilizer cleaners on them and I use normal soap on my hands.
 
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not to mention they screw up your skin and often have carcinogens in em depending on which one used. hand sanitizer makes my hands itch like mad.
There was last year an on going recall of contaminated hand sanitizers with wood grain alcohol.
 
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There was last year an on going recall of contaminated hand sanitizers with wood grain alcohol.
There was that indeed. And yes, sensitive skin types may have issues with the general way they dry out your skin. Never seen any evidence for carcinogens though.
 

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so it not just kill the germs but human too
It's unlikely to be truly lethal but it can be very irritating and have bad allergic impacts. And yes, in bad cases it can even be lethal.

Sounds like we just need to stop buying hand sanitizer from mexico, frankly.

And just use soap. Soap is king.
 

dgianstefani

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As someone who's a student of medicine, this bothers me greatly, and microbial resistance looks to be one of the next cliffs we fall off.

We seem so confident in our technology to save us, but the sad reality is that we are forcing ourselves into a situation where higher and higher levels of technology will be required to sustain lifestyles that used to be supported and possible just through things like natural resistance or basic medical intervention.

D0ajo8BWwAArCFZ.jpg
Microbial resistance to the same drugs.



Get used to face masks, you'll want access to them around long after Covid passes.
Personally I use a Respro Cinqro with swappable inner HEPA/DACC combo filter. The filters are good for about 70-80 hours of total use before you swap them. Only one i've found outside of proper respirators that will actually stop viral particulates.
Cinqro.png


Virophage technology may save us, but it's still early in it's life cycle of medical development.
 
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