I have 9900KF and 10700K today and I tested it in professional software (Adobe PS/LR/AE/PP, DaVinci, etc.). I'm sorry I can't give you the exact numbers (NDA), but I can say that i7-10700K really liked it!
No PLX bridges? Only 16 lanes PCIe by CPU and and limited storage support... WS Z390 Pro is good, but this...
And poor VRM heatsink. Of course, if you will use PL1/2 in Auto, it's no problem.
Still waiting RKL.
For this requirements ASUS can prepare custom BIOS with this functionality. For example, it's may be per-port USB control (on/off). But it's not always possible to implement read/write/load blocking for each USB port. And PS/2 will be problem solution if all USB ports are disabled.
Fully working Pentium Pro 200 MHz (256KB L2) & 96 MB SIMM & Tekram P6F40-B5. Works with custom Win XP (125 MB installer without checking of hardware configuration).