Assuming basic home use, such as Youtube streaming, gaming, etc, and an LGA 1700 board (so new, not looking at older tech )
I can see:
2.5GbE - I'm not sure what I would be connecting to.
S/PDIF - if you have a DAC, sure?
4 RAM slots - yes this makes sense for the future, even if you are installing 16GB today.
Thunderbolt connector - I'm not sure if there is anything I could use this for.
Fan headers - the worst motherboards have only 1, so I guess this is limiting in a lot of cases
USB - every motherboard has at least 1 5 gigabit USB port, but not all of them have USB-C. OTOH you could just buy a USB-A to USB-C cable if you really need one. Faster USB3.2 2x2 etc. seems nice on paper but in reality a lot of people are connecting a USB 2.0 camera or something, so the 10 gigabit and 20 gigabit stuff seems a bit.... superfluous?
PCIE - every LGA 1700 motherboard has PCI 4.0 x16, or PCI 5.0 x16, which seems fine, right?
SATA - most boards have 4 connectors, some have 6 or 8. 4 is enough for nearly everyone, obviously if you have a lot of hard drives then ... yeah
M.2 slots - this one looks like a relevant consideration in that if you have 1 M.2 drive then you are likely to want to add a second at one point, so one M.2 slot is very limiting at this point.
Multiple video outputs - a few have only 1, so I guess you'd need to double check if you need DisplayPort, but otoh you might well be using a discrete GPU anyway.
(Obviously there is heatsinks, VRM quality, chipless BIOS flashing, etc., to consider)
I can see:
2.5GbE - I'm not sure what I would be connecting to.
S/PDIF - if you have a DAC, sure?
4 RAM slots - yes this makes sense for the future, even if you are installing 16GB today.
Thunderbolt connector - I'm not sure if there is anything I could use this for.
Fan headers - the worst motherboards have only 1, so I guess this is limiting in a lot of cases
USB - every motherboard has at least 1 5 gigabit USB port, but not all of them have USB-C. OTOH you could just buy a USB-A to USB-C cable if you really need one. Faster USB3.2 2x2 etc. seems nice on paper but in reality a lot of people are connecting a USB 2.0 camera or something, so the 10 gigabit and 20 gigabit stuff seems a bit.... superfluous?
PCIE - every LGA 1700 motherboard has PCI 4.0 x16, or PCI 5.0 x16, which seems fine, right?
SATA - most boards have 4 connectors, some have 6 or 8. 4 is enough for nearly everyone, obviously if you have a lot of hard drives then ... yeah
M.2 slots - this one looks like a relevant consideration in that if you have 1 M.2 drive then you are likely to want to add a second at one point, so one M.2 slot is very limiting at this point.
Multiple video outputs - a few have only 1, so I guess you'd need to double check if you need DisplayPort, but otoh you might well be using a discrete GPU anyway.
(Obviously there is heatsinks, VRM quality, chipless BIOS flashing, etc., to consider)