I saw that you guys have a how-to for setting up a single GPU client but nothing (that I saw anyway) for multiple. I was frustrated with homework at 2:45 in the morning so I thought I'd type this up Any questions or corrections, let me know and I'll address them. Notes: I based this off using the systray client, however setup should be similar for the console. You must turn SLI to OFF for this to work. You can leave the bridges connected, just be sure SLI is OFF in the control center. You will need to extend your desktop to the second card (and third and fourth etc) in order to activate the card to fold on it. XP users can just extend, Vista users need DUMMY PLUGS on each card to extend the desktop as shown HERE. Downside is your mouse pointer can run away on you, but if it does, just drag your mouse to the left until it reappears Sometimes, the GPU IDs and the actual cards get confused in software, i.e. gpu 0 ends up being the second card and gpu 1 ends up being the first card (this happened to me). Cause is unknown but it doesn't hurt anything. Just confusing is all. 1. DOWNLOAD GPU2 systray client, I used the standard one not the "special" nvidia one since you should leave the viewer closed anyway! Slows stuff down http://folding.stanford.edu/English/DownloadWinOther 2. INSTALL just follow the directions. Not too hard here 3. DUPLICATE For XP: Go to C:\Documents and Settings\<username>\Application Data and make a second copy of the Folding@Home-gpu folder and call it Folding@home-gpu-1 For VISTA: Go to C:\Users\<username>\AppData\Roaming and make a second copy of the Folding@Home-gpu folder and call it Folding@home-gpu-1 4. CREATE SHORTCUTS Ignore the shortcut that the installer made in your start menu. Create a new shortcut on your desktop (or wherever you prefer) using THIS INFO: For XP: TARGET (Include everything in bold): "C:\Program Files\Folding@home\Folding@home-gpu\Folding@home.exe" -gpu 0 START IN (include everything in bold): "C:\Documents and Settings\username\Application Data\Folding@home-gpu" For VISTA: TARGET (Include everything in bold): "C:\Program Files\Folding@home\Folding@home-gpu\Folding@home.exe" -gpu 0 note Vista x64 users: Program Files will be Program Files (x86) START IN (include everything in bold): "C:\Users\username\AppData\Folding@home-gpu" Repeat for the second client, except change the TARGET to have -gpu 1 on the end and START IN to have -1 on the end, like so: In XP "C:\Documents and Settings\username\Application Data\Folding@home-gpu-1" or in VISTA "C:\Users\username\AppData\Folding@home-gpu-1" 5. CONFIGURE Start the shortcut for your first client. It will display a control panel. Put in your F@H username, team number, and (if you have one) passkey. Go to the advanced tab, make sure the machine ID is set to 1, UNLESS you have a CPU client (i.e. SMP) on your CPU. In which case, use the next available ID number (probably 2 if you are running just one CPU client). I suggest setting priority to "slightly higher" as well. CPU usage percent should be all the way up for max performance, note that it probably will not use more than a few percent if any in actual usage. Hit OK, your first client should be running. Start the second client. Set your username, team number, etc... everything the same as the first client EXCEPT set the machine ID to the next ID number. Voila! Both should be working now. Good job 6. MONITORING To monitor the GPU clients in FAHmon, point FAHmon to the START IN folders of the clients.