I really wished ATI and Intel worked out on Crossfire for the Intel Seaberg 5400. We're getting to see the workstation giants, TYAN, SM, ASUS come up with WS boards with 2x PCI-E 2.0.
With relevence to the topic, with ATI Crossfire, 5400 based WS boards could become inexpensive but amazing alternatives for the elite Skulltrail. Sure, 4x PCI-E slots but we still get to use 2x Xeons. No OC'ing too but with the amount of raw processing power at disposal, we wouldn't need OC'ing too when used with 2 Harpertown chips. At least (2x E5430 ($1200) + Seaberg based board from SM (~$300) looks a nice inexpensive alternative to a Skulltrail ( > $300 (I expect)) + 2x Core 2 Extreme QX9770 (~$2000?)
If the 5400 does get Crossfire support, 2x HD3870 X2 cards paired with this will form a superb value alternative to a Skulltrail setup.