• Welcome to TechPowerUp Forums, Guest! Please check out our forum guidelines for info related to our community.

Print New Organs Using 3D Stem Cells

Joined
Jun 17, 2007
Messages
7,326 (1.89/day)
Likes
995
Location
C:\Program Files (x86)\Aphexdreamer\
System Name Unknown
Processor AMD Bulldozer FX8320 @ 4.4Ghz
Motherboard Asus Crosshair V
Cooling XSPC Raystorm 750 EX240 for CPU
Memory 8 GB CORSAIR Vengeance Red DDR3 RAM 1922mhz (10-11-9-27)
Video Card(s) XFX R9 290
Storage Samsung SSD 254GB and Western Digital Caviar Black 1TB 64MB Cache SATA 6.0Gb/s
Display(s) AOC 23" @ 1920x1080 + Asus 27" 1440p
Case HAF X
Audio Device(s) X Fi Titanium 5.1 Surround Sound
Power Supply 750 Watt PP&C Silencer Black
Software Windows 8.1 Pro 64-bit
#1
File this under unexpectedly cool: organs you don’t harvest, but instead print using an honest-to-goodness printer, just as you might words on paper, except in this case, the “words” are actual stem cells that could save someone’s life.

Let’s talk about 3D printers for a moment: high-tech contraptions that let you craft three-dimensional objects with a computer aided design program, then render them in the real world as instantly usable objects with, say, a little powder and some binding material. We’ve used such devices to make everything from jewelry and full-color models of human faces to smartphone cases and battery-powered motors. Scan an existing physical object like a crescent wrench into a computer and a 3D printer can completely replicate it just a short while later, no assembly required, right down to the adjustable jaws and cylindrical track.

Now imagine a device that could print new organs on demand using cells in lieu of ink (call it “bio-ink,” because the scientists do). It’s part of a process known as biofabrication: assembling the essential cellular building blocks of organs using the mechanical exactness of computer-driven, three-dimensional printing technology.

Say you need a new trachea, a part of the body we’ve already managed to replicate using stem cells and successfully transplant to a human with late-stage tracheal cancer (I’m not making that up or exaggerating). With a 3D printer and a bunch of stem cell-saturated bio-ink, you might be able to just print that trachea on demand thanks to a new technique that lets you pass human embryonic stem cells (hESCs) through a printer nozzle without destroying them.

A team of researchers from Scotland announced Monday that they’d finally managed to get an inkjet-style printer to craft an organic 3D object. Not an actual organ (well, not yet), but these scientists claim they’ve been able to clear a crucial hurdle: getting hESCs, prized for their ability to become cells of any tissue type, to survive the printing process.

The solution involved rejiggering the way the inkjet-style 3D printer worked, specifically the printing valve, which had to be tweaked to ever-so-gently deposit blobs of hESCs in programmable patterns without compromising the viability and functionality of the cells themselves. The researchers figured out how to do this using two types of bio-inks as well as allow for independent control of the amount in each droplet (with considerable control granularity — down to less than five cells per droplet). The results of the experiment were just published in the bio-science print and online journal Biofabrication.

“We are able to print millions of cells within minutes,” said paper co-author Will Shu of the Heriot-Watt University in Edinburgh, reports Agence France-Presse. Shu adds that the printer is comparable in size to a garden variety desktop laser printer.

It’s not like we haven’t printed cells before — we’ve been able to print stuff as crazy-sounding as DNA for years. But getting hESCs through a 3D printer nozzle successfully using a method that allows how they emerge and in what amounts to be controlled precisely without compromising their viability and rendering them as 3D objects — that’s crazy-cool future science. And though it’ll be some time before we’re printing stuff like human tracheas, to say nothing of organs that require complex networks of blood vessels to sustain the tissue, we’re a momentous step closer after this breakthrough.

What’s more, the immediate benefits extend well beyond human organ genesis: Next up, Shu and team intend to print 3D liver tissue, which Shu hopes could eliminate the use of non-human animals in laboratory drug tests.



Read more: Source
 
Joined
Mar 2, 2011
Messages
776 (0.31/day)
Likes
844
Location
Omaha, NE
System Name "The Gift"
Processor Intel Core i5 2500k
Motherboard ASUS Maximus iV Gene-Z/Gen 3
Cooling Cryorig M9i
Memory G. Skill 8GB(2x4GB) Ripjaws "X" Series - DDR3 1600
Video Card(s) HIS HD 7950 IceQ Turbo 3GB
Storage WD Velociraptor Enterprise Edition - 300GB
Display(s) HP e232
Case Fractal Design - Arc Mini
Power Supply Corsair TX650W
Mouse Logitech T400 Zone Touch Mouse
Keyboard HP KBRF57711 Wireless Keyboard
Software Ubuntu 16.04.3 LTS/Windows 7 Professional - 64 bit(GOG/Steam Only)
#2
Reminds me of the 're-creation' of the 5th element that 'fell out of the sky' - interesting movie with serious biblical undertones...I think I'd pass on printed organs. Frankly...for myself, and I don't speak for anyone else, I'll just take the years given and move along.

I'm an alien and a stranger to this planet and I like it this way.

:),

Liquid Cool
 
Joined
Aug 17, 2009
Messages
2,553 (0.83/day)
Likes
1,013
Location
United States
System Name Aluminum Mallard
Processor Intel i7 940
Motherboard ASUS Rampage III: Gene
Cooling Noctua C-12P
Memory 6GB Corsair Dominator DDR3
Video Card(s) ASUS HD5870
Storage OCZ Vertex 2 60GB SSD, 2 x Seagate Barracuda 7200.12 in RAID0
Display(s) HP w2338h
Case Corsair 700D
Audio Device(s) On Board
Power Supply Corsair TX850
Software Win7 Ult 64 bit
Benchmark Scores 31 FPS in Dalaran.
#3
Finally, the end of trust-fund children is in our sight.

The rest of you poor f***s are SOL.