waterblock on cpu?

I recently unpluged my quick connects, and I am not sure if they areplugged in the same as before.. Does it matter , in general, which way the coolant flows at the cpu block?
This is an easy fix if the need arises to swap.. and I did not notice a temp change.. thanks

fyi I use a Corsair N500(Nautilas500)

 

From the look of it, I'd say no. The only blocks that matter are impingment blocks like the storm or other blocks that direct the flow to the center of the block over the core first. The block with the Nautilus looks like it just flows from one side to the other.