Im fine with only 2 M.2 Slots i dont have a lot of USB devices either maybe like 5.Honestly the only thing that bothers me personally about it is it does not have bios flashback I feel like every board should have it and the I/O really sucks I think it only has 2 m.2 and the usb situation is sad.
The TUF really isn't better so the 40 more it cost isn't worth it either.
Those are all a you thing though you have to make those kinds of decisions it's easy for me to say you should get a 250 board when it isn't coming out of my pocket.
Does the Mainboard even Support the 14600KF? Or do i would need to Update the Bios (which would be hard without Bios Flashback)