Got my new Radeon RX 6600 and it performs great. But I got tired real quick of the three stock 80mm fans screaming in my ear so I re-pasted and de-shrouded the card the following day after getting it. Now it's got 2 x 120mm Be Quiet SW3 fans hung on there and maximum speed at 1450rpm is only around 30dB (ridiculously quiet), with GPU hotspot temperatures around 82C max. And that's with a +20% power limit and memory overclock so it can't really get much hotter than that.
Anyway I reckon this 1080p beast machine won't see any further upgrades until I need more storage or upgrade the GPU again. Unlikely to be any time soon.