Sapphire's card is a low-profile PCB design which can be converted to an actual low-profile card by removing the analog VGA connector.
The card requires just a single slot in your system. Even though the heatsink covers a small area of the back of the card, I don't expect this to have any effect on installation in small form factor cases.
Display connectivity is one DVI port, one full size HDMI port and one removable analog VGA output. On higher-end AMD cards we usually see quite expansive display output options, the HD 6450 limits them slightly by using a DVI output that does not carry an analog VGA output signal. Nevertheless, you may still use up to three displays at the same time.
An HDMI sound device is included in the GPU, too. It is HDMI 1.4a compatible which includes HD audio and support for Blu-ray 3D movies. The DisplayPort interface is DisplayPort 1.2 compliant which allows the use of a DisplayPort hub to connect multiple monitors, or daisy chain them together.
You may combine up to two HD 6450 cards from any vendor in a multi-GPU CrossFire configuration. A physical CrossFire connector is not present, all multi-GPU data is transferred via the PCI-Express bus.
Pictured above are photos of the front and back, showing the disassembled board. High-res versions are also available (front, back). If you choose to use these images for voltmods etc, please include a link back to this site or let us post your article.