I just googled "disable windows defender"
Yes, you can disable Microsoft Defender Antivirus on Windows 10, and here's how.
www.windowscentral.com
If you did the gpedit.msc move go for the regedit move :
- Use the Windows key + R keyboard shortcut to open the Run command.
- Type regedit, and click OK to open the Registry.
- Browse the following path:
HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows Defender
- Right-click on the Windows Defender (folder) key, select New, and click on DWORD (32-bit) Value.
- Name the key DisableAntiSpyware and press Enter.
- Double-click the newly created key and set the value from 0 to 1.
- Click OK.
- Right-click on the Windows Defender (folder) key, select New, and click on Key.
- Name the key Real-Time Protection and press Enter.
- Right-click on the Real-Time Protection (folder) key, select New, and click on DWORD (32-bit) Value.
- Name the key DisableBehaviorMonitoring and press Enter.
- Double-click the newly created key and set the value from 0 to 1.
- Click OK.
- Right-click on the Real-Time Protection (folder) key, select New, and click on DWORD (32-bit) Value.
- Name the key DisableOnAccessProtection and press Enter.
- Double-click the newly created key and set the value from 0 to 1.
- Click OK.
- Right-click on the Real-Time Protection (folder) key, select New, and click on DWORD (32-bit) Value.
- Name the key DisableScanOnRealtimeEnable and press Enter.
- Double-click the newly created key and set the value from 0 to 1.
- Click OK.
After completing the steps, simply restart your computer to disable the Windows Defender Antivirus permanently.
If you change your mind, you can always revert the changes using the same instructions, but on
step No. 3, right-click the
DisableAntiSpyware key, and select
Delete. Then inside the
Windows Defender (folder) key, right-click the
Real-Time Protection (folder) key and select
Delete to remove key and its content. Finally, restart your device to complete reverting the changes.
You don't need third party programs to do this or else you are just lazy

Third party programs tend to let you think they can block telemetry. Ok but they tend to break the store and many things you could find useful by deleting them...
You want a good thing for your paranoia obsessions ?

Get a firewall (the windows one is just crap) and lose some time asking for ANY connections. It's time consumming the first days but once you got your firewall rules set up without having your system broken you are gold.
Also you don't need to have a 24/7 antivirus if you think you know what you are doing. Once a month download a trial from Kaspersky or Bitdefender (depends if you are more Russia or USA) and scan the whole system to be sure it's fine. A good program I know too is
Rogue Killer. Take the free version (no autoupdate, no custom scan) and run it once a month if you feel your computer is in danger

Some people want to cut all the microsoft telemetry but take 24/7 antispyware/antivirus which spy them all day long...that's nonsense.
I won't judge if you want to feel safe but the question is, is everything really safe with 24/7 programs scanning all your datas ? I still can't answer this. Up to you.
Edit : about firewalls I use
NetLimiter 4 Pro and it's doing the job. Many firewalls can do the job, it's just a bit of work being harassed by connections demands, checking what the services asking for internet are doing and all but it's a good move in my opinion.