hey man nothing much :) just kinda been on and off lately..alot to do with the site and stuff reviews all over the place its been tight schd..but im glad your back though..i mean your right u werent on that much either :P
The only settings that gives more or less performance @ the GPU client are: priority - use low, and cpu/gpu usage - use 100%.
I don't know witch cards are you folding at the moment, but OC gives some extra help. Folding OC is not like gaming OC. Don't try to compare them. All I can say is patience. Use rivatuner, don't OC mem. Concentrate in shaders.
Change the values, run the console. When you start getting UNSTABLE_MACHINE. Go back. That's your limit.