If you're running it now with SLIpatch and old drivers, it'll work with new HyperSLI and new drivers, as long as you disable the virtualization when you want to use Virtual Machines. Worst case scenario, when you want to run a VM, your SLI might not work until you turn off your VM and re-enable HyperSLI virtualization. What you'll do is: 1. make sure all your VMs are turned off 2. make sure your VMs don't automatically start at boot 3. install the new Nvidia drivers 4. reboot 5. run the HyperSLI 0.7 installer, press install or update or patch 6. reboot 7. open the HyperSLI Control Panel and make sure the box "Automatic disable Hypervisor when windows starts" box is checked. 8. reboot Edit: To clarify, you may need to close your VMs and enable hypervisor manually before you play a game with SLI. If you need your VMs open at all times, even while playing games, you may want to hold off on installing the new drivers until you know if HyperSLI 0.7 works how you want. That way, you only need to revert Hyper/SLIpatch and not the drivers, too.